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Novel betulin derivative induces anti-proliferative activity by G(2)/M phase cell cycle arrest and apoptosis in Huh7 cells

Betulin (BT) has been identified to exhibit potential benefits for treating hepatocellular carcinoma (HCC). The results of the present study demonstrated that a new semisynthetic derivative of BT, 3,28-di-(2-nitroxy-acetyl)-oxy-BT, may effectively decrease the viability of Huh7 cells. Mechanistic st...

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Библиографические подробности
Опубликовано в: :Oncol Lett
Главные авторы: Zhuo, Zhen-Jian, Xiao, Min-Jie, Lin, Hui-Ran, Luo, Jing, Wang, Tao
Формат: Artigo
Язык:Inglês
Опубликовано: D.A. Spandidos 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776954/
https://ncbi.nlm.nih.gov/pubmed/29434911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7575
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