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Novel betulin derivative induces anti-proliferative activity by G(2)/M phase cell cycle arrest and apoptosis in Huh7 cells

Betulin (BT) has been identified to exhibit potential benefits for treating hepatocellular carcinoma (HCC). The results of the present study demonstrated that a new semisynthetic derivative of BT, 3,28-di-(2-nitroxy-acetyl)-oxy-BT, may effectively decrease the viability of Huh7 cells. Mechanistic st...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Zhuo, Zhen-Jian, Xiao, Min-Jie, Lin, Hui-Ran, Luo, Jing, Wang, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776954/
https://ncbi.nlm.nih.gov/pubmed/29434911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7575
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