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Novel betulin derivative induces anti-proliferative activity by G(2)/M phase cell cycle arrest and apoptosis in Huh7 cells

Betulin (BT) has been identified to exhibit potential benefits for treating hepatocellular carcinoma (HCC). The results of the present study demonstrated that a new semisynthetic derivative of BT, 3,28-di-(2-nitroxy-acetyl)-oxy-BT, may effectively decrease the viability of Huh7 cells. Mechanistic st...

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Podrobná bibliografie
Vydáno v:Oncol Lett
Hlavní autoři: Zhuo, Zhen-Jian, Xiao, Min-Jie, Lin, Hui-Ran, Luo, Jing, Wang, Tao
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776954/
https://ncbi.nlm.nih.gov/pubmed/29434911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7575
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