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Novel betulin derivative induces anti-proliferative activity by G(2)/M phase cell cycle arrest and apoptosis in Huh7 cells
Betulin (BT) has been identified to exhibit potential benefits for treating hepatocellular carcinoma (HCC). The results of the present study demonstrated that a new semisynthetic derivative of BT, 3,28-di-(2-nitroxy-acetyl)-oxy-BT, may effectively decrease the viability of Huh7 cells. Mechanistic st...
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| Publicado en: | Oncol Lett |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
D.A. Spandidos
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5776954/ https://ncbi.nlm.nih.gov/pubmed/29434911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7575 |
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