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Promoter methylation of RB1, P15, P16, and MGMT and their impact on the clinical course of pilocytic astrocytomas

Promoter methylation of P15, P16, RB transcriptional corepressor 1 (RB1) and O-6-methylguanine-DNA methyltransferase (MGMT) impacts the prognosis of numerous glioma subtypes. However, whether promoter methylation of these genes also has an impact on the clinical course of pilocytic astrocytoma remai...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncol Lett
Hauptverfasser: Sippl, Christoph, Urbschat, Steffi, Kim, Yoo Jin, Senger, Sebastian, Oertel, Joachim, Ketter, Ralf
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776924/
https://ncbi.nlm.nih.gov/pubmed/29434855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7490
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