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Promoter methylation of RB1, P15, P16, and MGMT and their impact on the clinical course of pilocytic astrocytomas

Promoter methylation of P15, P16, RB transcriptional corepressor 1 (RB1) and O-6-methylguanine-DNA methyltransferase (MGMT) impacts the prognosis of numerous glioma subtypes. However, whether promoter methylation of these genes also has an impact on the clinical course of pilocytic astrocytoma remai...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Sippl, Christoph, Urbschat, Steffi, Kim, Yoo Jin, Senger, Sebastian, Oertel, Joachim, Ketter, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776924/
https://ncbi.nlm.nih.gov/pubmed/29434855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7490
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