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Sodium butyrate induces senescence and inhibits the invasiveness of glioblastoma cells

Sodium butyrate (SB), a short chain (C-4) saturated fatty acid, is present in the human bowel at increased concentrations (~2 mM) as a food metabolite. It has been demonstrated that SB exerts an anti-tumor effect as a histone deacetylase inhibitor; however, its precise mechanism of action remains to...

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Veröffentlicht in:Oncol Lett
Hauptverfasser: Nakagawa, Hidemitsu, Sasagawa, Satoru, Itoh, Kazuyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776921/
https://ncbi.nlm.nih.gov/pubmed/29434841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7518
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