Change in Neutrophil-to-lymphocyte ratio (NLR) in response to immune checkpoint blockade for metastatic renal cell carcinoma

BACKGROUND: An elevated Neutrophil-to-lymphocyte ratio (NLR) is associated with worse outcomes in several malignancies. However, its role with contemporary immune checkpoint blockade (ICB) is unknown. We investigated the utility of NLR in metastatic renal cell carcinoma (mRCC) patients treated with...

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Pubblicato in:J Immunother Cancer
Autori principali: Lalani, Aly-Khan A., Xie, Wanling, Martini, Dylan J., Steinharter, John A., Norton, Craig K., Krajewski, Katherine M., Duquette, Audrey, Bossé, Dominick, Bellmunt, Joaquim, Van Allen, Eliezer M., McGregor, Bradley A., Creighton, Chad J., Harshman, Lauren C., Choueiri, Toni K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776777/
https://ncbi.nlm.nih.gov/pubmed/29353553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-018-0315-0
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