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Change in Neutrophil-to-lymphocyte ratio (NLR) in response to immune checkpoint blockade for metastatic renal cell carcinoma

BACKGROUND: An elevated Neutrophil-to-lymphocyte ratio (NLR) is associated with worse outcomes in several malignancies. However, its role with contemporary immune checkpoint blockade (ICB) is unknown. We investigated the utility of NLR in metastatic renal cell carcinoma (mRCC) patients treated with...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Lalani, Aly-Khan A., Xie, Wanling, Martini, Dylan J., Steinharter, John A., Norton, Craig K., Krajewski, Katherine M., Duquette, Audrey, Bossé, Dominick, Bellmunt, Joaquim, Van Allen, Eliezer M., McGregor, Bradley A., Creighton, Chad J., Harshman, Lauren C., Choueiri, Toni K.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776777/
https://ncbi.nlm.nih.gov/pubmed/29353553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-018-0315-0
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