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Itraconazole attenuates hepatic gluconeogenesis and promotes glucose uptake by regulating AMPK pathway
The primarily metabolic abnormality in type 2 diabetes mellitus (T2DM) is the defect in gluconeogenesis and glucose uptake. Itraconazole (ITCZ) is a traditional azole drug with anti-fungal and anticancer properties. However, limited attention has been directed towards the contribution of ITCZ to hep...
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| Publicado no: | Exp Ther Med |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5776524/ https://ncbi.nlm.nih.gov/pubmed/29434820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.5602 |
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