Intracerebroventricular Administration of (192)IgG-Saporin Alters Expression of Microglia-Associated Genes in the Dorsal But Not Ventral Hippocampus

One of important aspects of development of Alzheimer’s disease is degeneration of septal cholinergic neurons that innervate the hippocampus. We took advantage of widely used model of cholinergic deficit in the hippocampus, intracerebroventricular administration of (192)IgG-saporin (Ig-saporin), to a...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Dobryakova, Yulia V., Kasianov, Artem, Zaichenko, Maria I., Stepanichev, Mikhail Y., Chesnokova, Ekaterina A., Kolosov, Petr M., Markevich, Vladimir A., Bolshakov, Alexey P.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776139/
https://ncbi.nlm.nih.gov/pubmed/29386992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00429
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