PK-PD Integration Modeling and Cutoff Value of Florfenicol against Streptococcus suis in Pigs

The aims of the present study were to establish optimal doses and provide an alternate CO(PD) for florfenicol against Streptococcus suis based on pharmacokinetic-pharmacodynamic integration modeling. The recommended dose (30 mg/kg b.w.) were administered in healthy pigs through intramuscular and int...

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Gardado en:
Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Lei, Zhixin, Liu, Qianying, Yang, Shuaike, Yang, Bing, Khaliq, Haseeb, Li, Kun, Ahmed, Saeed, Sajid, Abdul, Zhang, Bingzhou, Chen, Pin, Qiu, Yinsheng, Cao, Jiyue, He, Qigai
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776115/
https://ncbi.nlm.nih.gov/pubmed/29387013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00002
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