Pharmacokinetic and Pharmacodynamic Evaluation of Marbofloxacin and PK/PD Modeling against Escherichia coli in Pigs

The aim of this study was to evaluate the activity of marbofloxacin and establish the optimal dose regimens for decreasing the development of fluoroquinolone resistance in pigs against Escherichia coli with ex vivo pharmacokinetic/pharmacodynamic (PK/PD) modeling. The recommended dose (2 mg/kg body...

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Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Lei, Zhixin, Liu, Qianying, Xiong, Jincheng, Yang, Bing, Yang, Shuaike, Zhu, Qianqian, Li, Kun, Zhang, Shishuo, Cao, Jiyue, He, Qigai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566571/
https://ncbi.nlm.nih.gov/pubmed/28871226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00542
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