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Complement Factor H in AMD: Bridging Genetic Associations and Pathobiology

AMD is a complex multifactorial disease characterized in its early stages by lipoprotein accumulations in BrM, seen on fundoscopic exam as drusen, and in its late forms by neovascularization (“wet”) or geographic atrophy of the RPE cell layer (“dry”). Genetic studies have strongly supported a relati...

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Detalhes bibliográficos
Publicado no:Prog Retin Eye Res
Main Authors: Toomey, Christopher B., Johnson, Lincoln V., Rickman, Catherine Bowes
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776047/
https://ncbi.nlm.nih.gov/pubmed/28928087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.preteyeres.2017.09.001
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