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Complement Factor H in AMD: Bridging Genetic Associations and Pathobiology

AMD is a complex multifactorial disease characterized in its early stages by lipoprotein accumulations in BrM, seen on fundoscopic exam as drusen, and in its late forms by neovascularization (“wet”) or geographic atrophy of the RPE cell layer (“dry”). Genetic studies have strongly supported a relati...

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Bibliografiske detaljer
Udgivet i:Prog Retin Eye Res
Main Authors: Toomey, Christopher B., Johnson, Lincoln V., Rickman, Catherine Bowes
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776047/
https://ncbi.nlm.nih.gov/pubmed/28928087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.preteyeres.2017.09.001
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