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Inhibition of the CatSper Channel and NOX5 Enzyme Activity Affects the Functions of the Progesterone-Stimulated Human Sperm

BACKGROUND: Low levels of reactive oxygen species (ROS) and calcium are necessary for sperm function. NADPH oxidase 5 (NOX5) is a membrane enzyme which produces ROS. This enzyme is dependent on calcium for its activity. We investigated the importance of NOX5 and an important calcium channel (CatSper...

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Pubblicato in:Iran J Med Sci
Autori principali: Ghanbari, Hamideh, Keshtgar, Sara, Kazeroni, Marjaneh
Natura: Artigo
Lingua:Inglês
Pubblicazione: Iranian Journal of Medical Sciences 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5775990/
https://ncbi.nlm.nih.gov/pubmed/29398748
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