pH-sensitive amide proton transfer (APT) effect dominates the magnetization transfer asymmetry contrast during acute ischemia — Quantification of multi-pool contribution to in vivo CEST MRI

PURPOSE: To determine the origins of in vivo magnetization transfer (MT) asymmetry (MTR(asym)) contrast during acute ischemic stroke, particularly in the diffusion lesion, perfusion lesion and their mismatch using a middle cerebral artery occlusion (MCAO) rat model of acute stroke. METHODS: Adult ma...

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Detalhes bibliográficos
Publicado no:Magn Reson Med
Main Authors: Wu, Yin, Zhou, Iris Yuwen, Lu, Dongshuang, Manderville, Emiri, Lo, Eng H, Zheng, Hairong, Sun, Phillip Zhe
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5775916/
https://ncbi.nlm.nih.gov/pubmed/28733991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.26829
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