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Higher tacrolimus concentrations early after transplant reduce the risk of acute graft-versus-host disease in reduced-intensity allogeneic stem cell transplantation

There is significant variability in the serum concentrations of tacrolimus attained early post-transplant due to drug interactions and genomic variation. We evaluated whether tacrolimus concentrations early post-transplant correlate with incidence of acute graft-versus-host disease in 120 consecutiv...

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Détails bibliographiques
Publié dans:Bone Marrow Transplant
Auteurs principaux: Ganetsky, Alex, Shah, Arpita, Miano, Todd A., Hwang, Wei-Ting, He, Jiwei, Loren, Alison W., Hexner, Elizabeth O., Frey, Noelle V., Porter, David L., Reshef, Ran
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5775750/
https://ncbi.nlm.nih.gov/pubmed/26691423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bmt.2015.323
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