The fragile X mental retardation protein regulates tumor invasiveness-related pathways in melanoma cells

The fragile X mental retardation protein (FMRP) is lacking or mutated in patients with the fragile X syndrome (FXS), the most frequent form of inherited intellectual disability. FMRP affects metastasis formation in a mouse model for breast cancer. Here we show that FMRP is overexpressed in human mel...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zalfa, Francesca, Panasiti, Vincenzo, Carotti, Simone, Zingariello, Maria, Perrone, Giuseppe, Sancillo, Laura, Pacini, Laura, Luciani, Flavie, Roberti, Vincenzo, D'Amico, Silvia, Coppola, Rosa, Abate, Simona Osella, Rana, Rosa Alba, De Luca, Anastasia, Fiers, Mark, Melocchi, Valentina, Bianchi, Fabrizio, Farace, Maria Giulia, Achsel, Tilmann, Marine, Jean-Christophe, Morini, Sergio, Bagni, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5775405/
https://ncbi.nlm.nih.gov/pubmed/29144507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.521
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