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Helicobacter pylori-Induced HB-EGF Upregulates Gastrin Expression via the EGF Receptor, C-Raf, Mek1, and Erk2 in the MAPK Pathway

Helicobacter pylori is associated with hypergastrinemia, which has been linked to the development of gastric diseases. Although the molecular mechanism is not fully understood, H. pylori is known to modulate the Erk pathway for induction of gastrin expression. Herein we found that an epidermal growt...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Gunawardhana, Niluka, Jang, Sungil, Choi, Yun Hui, Hong, Youngmin A., Jeon, Yeong-Eui, Kim, Aeryun, Su, Hanfu, Kim, Ji-Hye, Yoo, Yun-Jung, Merrell, D. Scott, Kim, Jinmoon, Cha, Jeong-Heon
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5775237/
https://ncbi.nlm.nih.gov/pubmed/29379775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00541
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