Evolutionary mechanism leading to the multi-cagA genotype in Helicobacter pylori

Infection with CagA+ Helicobacter pylori strains is linked to an increased risk for gastric diseases, including gastric cancer. Recent evidence indicates that dynamic expansion and contraction of cagA copy number may serve as a novel mechanism to enhance disease development. Herein, comparative geno...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Su, Hanfu, Tissera, Kavinda, Jang, Sungil, Choi, Yun Hui, Kim, Aeryun, Cho, Yong-Joon, Li, Meiling, Gunawardhana, Niluka, Merrell, D. Scott, Ge, Linhu, Cha, Jeong-Heon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672019/
https://ncbi.nlm.nih.gov/pubmed/31371778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47240-2
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