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Evidence for allosteric effects on p53 oligomerization induced by phosphorylation
p53 is a tetrameric protein with a thermodynamically unstable deoxyribonucleic acid (DNA)‐binding domain flanked by intrinsically disordered regulatory domains that control its activity. The unstable and disordered segments of p53 allow high flexibility as it interacts with binding partners and perm...
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| Vydáno v: | Protein Sci |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
John Wiley and Sons Inc.
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5775181/ https://ncbi.nlm.nih.gov/pubmed/29124793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3344 |
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