Evidence for multiple modes of neutrophil serine protease recognition by the EAP family of Staphylococcal innate immune evasion proteins

Neutrophils contain high levels of chymotrypsin‐like serine proteases (NSPs) within their azurophilic granules that have a multitude of functions within the immune system. In response, the pathogen Staphylococcus aureus has evolved three potent inhibitors (Eap, EapH1, and EapH2) that protect the bac...

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Vydáno v:Protein Sci
Hlavní autoři: Stapels, Daphne A.C., Woehl, Jordan L., Milder, Fin J., Tromp, Angelino T., van Batenburg, Aernoud A., de Graaf, Wilco C., Broll, Samuel C., White, Natalie M., Rooijakkers, Suzan H.M., Geisbrecht, Brian V.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5775164/
https://ncbi.nlm.nih.gov/pubmed/29114958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3342
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