Physiologic Mitochondrial Fragmentation Is a Normal Cardiac Adaptation to Increased Energy Demand

RATIONALE: Mitochondria play a dual role in the heart, responsible for meeting energetic demands and regulating cell death. Paradigms have held that mitochondrial fission and fragmentation are the result of pathologic stresses such as ischemia, are an indicator of poor mitochondrial health, and lead...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Coronado, Michael, Fajardo, Giovanni, Nguyen, Kim, Zhao, Mingming, Kooiker, Kristina, Jung, Gwanghyun, Hu, Dong-Qing, Reddy, Sushma, Sandoval, Erik, Stotland, Aleksandr, Gottlieb, Roberta A., Bernstein, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5775047/
https://ncbi.nlm.nih.gov/pubmed/29233845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.310725
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