Chemical proteomics reveals soluble epoxide hydrolase as a therapeutic target for ocular neovascularization

The standard-of-care therapeutics for the treatment of ocular neovascular diseases like wet age-related macular degeneration (AMD) are biologics targeting vascular endothelial growth factor signaling. There are currently no FDA approved small molecules for treating these blinding eye diseases. There...

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I publikationen:ACS Chem Biol
Huvudupphovsmän: Sulaiman, Rania S., Park, Bomina, Babu, Sardar Pasha Sheik Pran, Si, Yubing, Kharwadkar, Rakshin, Mitter, Sayak K., Lee, Bit, Sun, Wei, Qi, Xiaoping, Boulton, Michael E., Meroueh, Samy, Fei, Xiang, Seo, Seung-Yong, Corson, Timothy W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5775043/
https://ncbi.nlm.nih.gov/pubmed/29193961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00854
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