Disagreements between central clinical events committee and site investigator assessments of myocardial infarction endpoints in an international clinical trial: review of the PURSUIT study

BACKGROUND: Limited information has been published regarding how specific processes for event adjudication can affect event rates in trials. We reviewed nonfatal myocardial infarctions (MIs) reported by site investigators in the international Platelet Glycoprotein IIb/IIIa in Unstable Angina: Recept...

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Hlavní autoři: Mahaffey, Kenneth W, Harrington, Robert A, Akkerhuis, Martijn, Kleiman, Neal S, Berdan, Lisa G, Crenshaw, Brian S, Tardiff, Barbara E, Granger, Christopher B, DeJong, Ingrid, Bhapkar, Manju, Widimsky, Petr, Corbalon, Ramón, Lee, Kerry L, Deckers, Jaap W, Simoons, Maarten L, Topol, Eric J, Califf, Robert M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2001
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC57750/
https://ncbi.nlm.nih.gov/pubmed/11806794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cvm-2-4-187
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