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Disagreements between central clinical events committee and site investigator assessments of myocardial infarction endpoints in an international clinical trial: review of the PURSUIT study

BACKGROUND: Limited information has been published regarding how specific processes for event adjudication can affect event rates in trials. We reviewed nonfatal myocardial infarctions (MIs) reported by site investigators in the international Platelet Glycoprotein IIb/IIIa in Unstable Angina: Recept...

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Autori principali: Mahaffey, Kenneth W, Harrington, Robert A, Akkerhuis, Martijn, Kleiman, Neal S, Berdan, Lisa G, Crenshaw, Brian S, Tardiff, Barbara E, Granger, Christopher B, DeJong, Ingrid, Bhapkar, Manju, Widimsky, Petr, Corbalon, Ramón, Lee, Kerry L, Deckers, Jaap W, Simoons, Maarten L, Topol, Eric J, Califf, Robert M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC57750/
https://ncbi.nlm.nih.gov/pubmed/11806794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cvm-2-4-187
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