Identification of a Small Molecule That Compromises the Structural Integrity of Viroplasms and Rotavirus Double-Layered Particles

Despite the availability of two attenuated vaccines, rotavirus (RV) gastroenteritis remains an important cause of mortality among children in developing countries, causing about 215,000 infant deaths annually. Currently, there are no specific antiviral therapies available. RV is a nonenveloped virus...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Eichwald, Catherine, De Lorenzo, Giuditta, Schraner, Elisabeth M., Papa, Guido, Bollati, Michela, Swuec, Paolo, de Rosa, Matteo, Milani, Mario, Mastrangelo, Eloise, Ackermann, Mathias, Burrone, Oscar R., Arnoldi, Francesca
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2018
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774888/
https://ncbi.nlm.nih.gov/pubmed/29142132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01943-17
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