An Inhibitory Motif on the 5’UTR of Several Rotavirus Genome Segments Affects Protein Expression and Reverse Genetics Strategies

Rotavirus genome consists of eleven segments of dsRNA, each encoding one single protein. Viral mRNAs contain an open reading frame (ORF) flanked by relatively short untranslated regions (UTRs), whose role in the viral cycle remains elusive. Here we investigated the role of 5’UTRs in T7 polymerase-dr...

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Gepubliceerd in:PLoS One
Hoofdauteurs: De Lorenzo, Giuditta, Drikic, Marija, Papa, Guido, Eichwald, Catherine, Burrone, Oscar R., Arnoldi, Francesca
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112996/
https://ncbi.nlm.nih.gov/pubmed/27846320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166719
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