β-d-N(4)-Hydroxycytidine Is a Potent Anti-alphavirus Compound That Induces a High Level of Mutations in the Viral Genome

Venezuelan equine encephalitis virus (VEEV) is a representative member of the New World alphaviruses. It is transmitted by mosquito vectors and causes highly debilitating disease in humans, equids, and other vertebrate hosts. Despite a continuous public health threat, very few compounds with anti-VE...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Urakova, Nadya, Kuznetsova, Valeriya, Crossman, David K., Sokratian, Arpine, Guthrie, David B., Kolykhalov, Alexander A., Lockwood, Mark A., Natchus, Michael G., Crowley, Michael R., Painter, George R., Frolova, Elena I., Frolov, Ilya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774879/
https://ncbi.nlm.nih.gov/pubmed/29167335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01965-17
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