Current or recent smoking is associated with more variable telomere length in prostate stromal cells and prostate cancer cells

BACKGROUND: Current and recent smoking have been associated with a greater risk of prostate cancer recurrence and mortality, though the underlying mechanism is unknown. METHODS: To determine if telomere shortening, which has been associated with poor outcomes, may be a potential underlying mechanism...

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Veröffentlicht in:Prostate
Hauptverfasser: Joshu, Corinne E, Peskoe, Sarah B, Heaphy, Christopher M, Kenfield, Stacey A, Mucci, Lorelei A, Giovannucci, Edward L, Stampfer, Meir J, Yoon, Ghilsuk, Lee, Thomas K, Hicks, Jessica L, De Marzo, Angelo M, Meeker, Alan K, Platz, Elizabeth A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774625/
https://ncbi.nlm.nih.gov/pubmed/29164645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23462
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