Prostate stromal cell telomere shortening is associated with risk of prostate cancer in the placebo arm of the Prostate Cancer Prevention Trial

BACKGROUND: Telomeres are repetitive nucleoproteins that help maintain chromosomal stability by inhibiting exonucleolytic degradation, prohibiting inappropriate homologous recombination, and preventing chromosomal fusions by suppressing double-strand break signals. We recently observed that men trea...

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Publicat a:Prostate
Autors principals: Heaphy, Christopher M., Gaonkar, Gaurav, Peskoe, Sarah B., Joshu, Corinne E., De Marzo, Angelo M., Lucia, M. Scott, Goodman, Phyllis J., Lippman, Scott M., Thompson, Ian M., Platz, Elizabeth A., Meeker, Alan K.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475463/
https://ncbi.nlm.nih.gov/pubmed/25893825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22997
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