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Prostate stromal cell telomere shortening is associated with risk of prostate cancer in the placebo arm of the Prostate Cancer Prevention Trial

BACKGROUND: Telomeres are repetitive nucleoproteins that help maintain chromosomal stability by inhibiting exonucleolytic degradation, prohibiting inappropriate homologous recombination, and preventing chromosomal fusions by suppressing double-strand break signals. We recently observed that men trea...

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Detalles Bibliográficos
Publicado en:Prostate
Main Authors: Heaphy, Christopher M., Gaonkar, Gaurav, Peskoe, Sarah B., Joshu, Corinne E., De Marzo, Angelo M., Lucia, M. Scott, Goodman, Phyllis J., Lippman, Scott M., Thompson, Ian M., Platz, Elizabeth A., Meeker, Alan K.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4475463/
https://ncbi.nlm.nih.gov/pubmed/25893825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22997
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