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Hypoxia inhibits TRAIL-induced tumor cell apoptosis: Involvement of lysosomal cathepsins

Tumor hypoxia interferes with the efficacy of chemotherapy, radiotherapy, and tumor necrosis factor-α. TRAIL (tumor necrosis factor-related apoptosis inducing ligand) is a potent apoptosis inducer that limits tumor growth without damaging normal cells and tissues in vivo. We present evidence for a c...

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Bibliografische gegevens
Gepubliceerd in:Apoptosis
Hoofdauteurs: Nagaraj, Nagathihalli S., Vigneswaran, Nadarajah, Zacharias, Wolfgang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774619/
https://ncbi.nlm.nih.gov/pubmed/17136492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-006-0490-1
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