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Hypoxia inhibits TRAIL-induced tumor cell apoptosis: Involvement of lysosomal cathepsins
Tumor hypoxia interferes with the efficacy of chemotherapy, radiotherapy, and tumor necrosis factor-α. TRAIL (tumor necrosis factor-related apoptosis inducing ligand) is a potent apoptosis inducer that limits tumor growth without damaging normal cells and tissues in vivo. We present evidence for a c...
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| Publicado no: | Apoptosis |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5774619/ https://ncbi.nlm.nih.gov/pubmed/17136492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-006-0490-1 |
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