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Folate deficiency and aberrant DNA methylation and expression of FHIT gene were associated with cervical pathogenesis
Aberrant DNA methylation is a recognized feature in various types of human cancer, and folate has a vital role in the epigenetics of mammalian cells by supplying methyl groups for DNA methylation reactions. Fragile histidine triad (FHIT) is a tumor suppressor gene that is frequently silenced in cerv...
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| Veröffentlicht in: | Oncol Lett |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
D.A. Spandidos
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5774424/ https://ncbi.nlm.nih.gov/pubmed/29434897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7471 |
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