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Folate deficiency and aberrant DNA methylation and expression of FHIT gene were associated with cervical pathogenesis

Aberrant DNA methylation is a recognized feature in various types of human cancer, and folate has a vital role in the epigenetics of mammalian cells by supplying methyl groups for DNA methylation reactions. Fragile histidine triad (FHIT) is a tumor suppressor gene that is frequently silenced in cerv...

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Bibliografiske detaljer
Udgivet i:Oncol Lett
Main Authors: Li, Qiaoling, Ding, Ling, Jing, Nan, Liu, Chunliang, Yang, Zuokai, Chen, Fang, Hou, Lifang, Wang, Jintao
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774424/
https://ncbi.nlm.nih.gov/pubmed/29434897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7471
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