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A distinctive histidine residue is essential for in vivo glycation-inactivation of human CD59 transgenically expressed in mice erythrocytes: Implications for human diabetes complications

Clinical and experimental evidences support a link between the complement system and the pathogenesis of diabetes complications. CD59, an extracellular cell membrane-anchored protein, inhibits formation of the membrane attack complex (MAC), the main effector of complement-mediated tissue damage. Thi...

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Foilsithe in:Am J Hematol
Main Authors: Sahoo, Rupam, Ghosh, Pamela, Chorev, Michael, Halperin, Jose A
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774238/
https://ncbi.nlm.nih.gov/pubmed/28815695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.24886
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