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Prochemerin cleavage by factor XIa links coagulation and inflammation

Chemerin is a chemoattractant and adipokine that circulates in blood as inactive prochemerin (chem163S). Chem163S is activated by a series of C-terminal proteolytic cleavages resulting in diverse chemerin forms with different levels of activity. We screened a panel of proteases in the coagulation, f...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Blood
Hauptverfasser: Ge, Xiaomei, Yamaguchi, Yasuto, Zhao, Lei, Bury, Loredana, Gresele, Paolo, Berube, Caroline, Leung, Lawrence L., Morser, John
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774209/
https://ncbi.nlm.nih.gov/pubmed/29158361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-07-792580
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