Combination Therapy Strategy of Quorum Quenching Enzyme and Quorum Sensing Inhibitor in Suppressing Multiple Quorum Sensing Pathways of P. aeruginosa

The threat of antibiotic resistant bacteria has called for alternative antimicrobial strategies that would mitigate the increase of classical resistance mechanism. Many bacteria employ quorum sensing (QS) to govern the production of virulence factors and formation of drug-resistant biofilms. Targeti...

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Vydáno v:Sci Rep
Hlavní autoři: Fong, July, Zhang, Chaodong, Yang, Renliang, Boo, Zhao Zhi, Tan, Soon Keat, Nielsen, Thomas E., Givskov, Michael, Liu, Xue-Wei, Bin, Wu, Su, Haibin, Yang, Liang
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773576/
https://ncbi.nlm.nih.gov/pubmed/29348452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19504-w
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