Exclusion from spheroid formation identifies loss of essential cell-cell adhesion molecules in colon cancer cells

Many cell lines derived from solid cancers can form spheroids, which recapitulate tumor cell clusters and are more representative of the in vivo situation than 2D cultures. During spheroid formation, a small proportion of a variety of different colon cancer cell lines did not integrate into the sphe...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Stadler, Mira, Scherzer, Martin, Walter, Stefanie, Holzner, Silvio, Pudelko, Karoline, Riedl, Angelika, Unger, Christine, Kramer, Nina, Weil, Beatrix, Neesen, Jürgen, Hengstschläger, Markus, Dolznig, Helmut
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773514/
https://ncbi.nlm.nih.gov/pubmed/29348601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19384-0
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