Exclusion from spheroid formation identifies loss of essential cell-cell adhesion molecules in colon cancer cells

Many cell lines derived from solid cancers can form spheroids, which recapitulate tumor cell clusters and are more representative of the in vivo situation than 2D cultures. During spheroid formation, a small proportion of a variety of different colon cancer cell lines did not integrate into the sphe...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Stadler, Mira, Scherzer, Martin, Walter, Stefanie, Holzner, Silvio, Pudelko, Karoline, Riedl, Angelika, Unger, Christine, Kramer, Nina, Weil, Beatrix, Neesen, Jürgen, Hengstschläger, Markus, Dolznig, Helmut
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773514/
https://ncbi.nlm.nih.gov/pubmed/29348601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19384-0
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