Activation of Ca(2+)-sensing receptor as a protective pathway to reduce Cadmium-induced cytotoxicity in renal proximal tubular cells

Cadmium (Cd), as an extremely toxic metal could accumulate in kidney and induce renal injury. Previous studies have proved that Cd impact on renal cell proliferation, autophagy and apoptosis, but the detoxification drugs and the functional mechanism are still in study. In this study, we used mouse r...

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Pubblicato in:Sci Rep
Autori principali: Gu, Jie, Dai, Shuya, Liu, Yanmin, Liu, Haitao, Zhang, Yao, Ji, Xingqi, Yu, Feng, Zhou, Yang, Chen, Liang, Tse, William Ka Fai, Wong, Chris Kong Chu, Chen, Binghai, Shi, Haifeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773512/
https://ncbi.nlm.nih.gov/pubmed/29348484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19327-9
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