Relaxin reverses inflammatory and immune signals in aged hearts

BACKGROUND: ‘Healthy’ aging drives structural and functional changes in the heart including maladaptive electrical remodeling, fibrosis and inflammation, which lower the threshold for cardiovascular diseases such as heart failure (HF) and atrial fibrillation (AF). Despite mixed results in recent cli...

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Udgivet i:PLoS One
Main Authors: Martin, Brian, Gabris-Weber, Beth Ann, Reddy, Rajiv, Romero, Guillermo, Chattopadhyay, Ansuman, Salama, Guy
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773192/
https://ncbi.nlm.nih.gov/pubmed/29346407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190935
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