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Identification of pain categories associated with change in pain in patients receiving placebo: data from two phase 3 randomized clinical trials in symptomatic knee osteoarthritis

BACKGROUND: Pain is the principal clinical symptom of osteoarthritis (OA), and development of safe and effective analgesics for OA pain is needed. Drug development of new analgesics for OA pain is impaired by substantial change in pain in patients receiving placebo, and more data describing clinical...

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Dettagli Bibliografici
Pubblicato in:BMC Musculoskelet Disord
Autori principali: Bihlet, Asger Reinstrup, Byrjalsen, Inger, Bay-Jensen, Anne-Christine, Andersen, Jeppe Ragnar, Christiansen, Claus, Riis, Bente Juel, Valter, Ivo, Karsdal, Morten A., Hochberg, Marc C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773024/
https://ncbi.nlm.nih.gov/pubmed/29343266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-018-1938-5
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