Overcoming the Limits of Hypoxia in Photodynamic Therapy: A Carbonic Anhydrase IX-Targeted Approach

A major challenge in photodynamic cancer therapy (PDT) is avoiding PDT-induced hypoxia, which can lead to cancer recurrence and progression through activation of various angiogenic factors and significantly reduce treatment outcomes. Reported here is an acetazolamide (AZ)-conjugated BODIPY photosens...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Jung, Hyo Sung, Han, Jiyou, Shi, Hu, Koo, Seyoung, Singh, Hardev, Kim, Hyo-Jin, Sessler, Jonathan L., Lee, Jin Yong, Kim, Jong-Hoon, Kim, Jong Seung
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772932/
https://ncbi.nlm.nih.gov/pubmed/28459562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b02396
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