Lysosome-associated membrane protein 2 (LAMP-2) expression induced by miR-194-5p downregulation contributes to sunitinib resistance in human renal cell carcinoma cells

Sunitinib is a tyrosine kinase inhibitor that is used as the primary treatment in metastatic renal cell carcinoma (RCC). The main difficulty associated with its use is the development of drug resistance. In the present study, ACHN cells, a human renal cell carcinoma cell line, were used to establish...

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Dades bibliogràfiques
Publicat a:Oncol Lett
Autors principals: Yumioka, Tetsuya, Osaki, Mitsuhiko, Sasaki, Ryo, Yamaguchi, Noriya, Onuma, Kunishige, Iwamoto, Hideto, Morizane, Shuichi, Honda, Masashi, Takenaka, Atsushi, Okada, Futoshi
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2018
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772808/
https://ncbi.nlm.nih.gov/pubmed/29399154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7423
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