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Lysosome-associated membrane protein 2 (LAMP-2) expression induced by miR-194-5p downregulation contributes to sunitinib resistance in human renal cell carcinoma cells

Sunitinib is a tyrosine kinase inhibitor that is used as the primary treatment in metastatic renal cell carcinoma (RCC). The main difficulty associated with its use is the development of drug resistance. In the present study, ACHN cells, a human renal cell carcinoma cell line, were used to establish...

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Bibliografiske detaljer
Udgivet i:Oncol Lett
Main Authors: Yumioka, Tetsuya, Osaki, Mitsuhiko, Sasaki, Ryo, Yamaguchi, Noriya, Onuma, Kunishige, Iwamoto, Hideto, Morizane, Shuichi, Honda, Masashi, Takenaka, Atsushi, Okada, Futoshi
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772808/
https://ncbi.nlm.nih.gov/pubmed/29399154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7423
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