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Relaxin ameliorates high glucose-induced cardiomyocyte hypertrophy and apoptosis via the Notch1 pathway

The present study aimed to investigate the role of relaxin (RLX) on high glucose (HG)-induced cardiomyocyte hypertrophy and apoptosis, as well as the possible molecular mechanism. H9c2 cells were exposed to 33 mmol/l HG with or without RLX (100 nmol/ml). Cell viability, apoptosis, oxidative stress,...

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Bibliografiske detaljer
Udgivet i:Exp Ther Med
Main Authors: Wei, Xiao, Yang, Yuan, Jiang, Yin-Jiu, Lei, Jian-Ming, Guo, Jing-Wen, Xiao, Hua
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772593/
https://ncbi.nlm.nih.gov/pubmed/29399073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.5448
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