Breviscapine ameliorates hypertrophy of cardiomyocytes induced by high glucose in diabetic rats via the PKC signaling pathway

AIM: To investigate the influence of breviscapine on high glucose-induced hypertrophy of cardiomyocytes and the relevant mechanism in vitro and in vivo. METHODS: Cultured neonatal cardiomyocytes were divided into i) control; ii) high glucose concentrations; iii) high glucose+PKC inhibitor Ro-31-8220...

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Bibliographic Details
Main Authors: Wang, Min, Zhang, Wen-bin, Zhu, Jun-hui, Fu, Guo-sheng, Zhou, Bin-quan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2009
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006682/
https://ncbi.nlm.nih.gov/pubmed/19597526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.95
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