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Visualization of barriers and obstacles to molecular diffusion in live cells by spatial pair-cross-correlation in two dimensions

Despite recent advances in optical super-resolution, we lack a method that can visualize the path followed by diffusing molecules in the cytoplasm or in the nucleus of cells. Fluorescence correlation spectroscopy (FCS) provides molecular dynamics at the single molecule level by averaging the behavio...

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Библиографические подробности
Опубликовано в: :Biomed Opt Express
Главные авторы: Malacrida, Leonel, Hedde, Per Niklas, Ranjit, Suman, Cardarelli, Francesco, Gratton, Enrico
Формат: Artigo
Язык:Inglês
Опубликовано: Optical Society of America 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772584/
https://ncbi.nlm.nih.gov/pubmed/29359105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.9.000303
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