Impact of Concurrent Genomic Alterations Detected by Comprehensive Genomic Sequencing on Clinical Outcomes in East-Asian Patients with EGFR-Mutated Lung Adenocarcinoma

Next-generation sequencing (NGS) has enabled comprehensive detection of genomic alterations in lung cancer. Ethnic differences may play a critical role in the efficacy of targeted therapies. The aim of this study was to identify and compare genomic alterations of lung adenocarcinoma between Japanese...

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Published in:Sci Rep
Main Authors: Sato, Seijiro, Nagahashi, Masayuki, Koike, Terumoto, Ichikawa, Hiroshi, Shimada, Yoshifumi, Watanabe, Satoshi, Kikuchi, Toshiaki, Takada, Kazuki, Nakanishi, Ryota, Oki, Eiji, Okamoto, Tatsuro, Akazawa, Kouhei, Lyle, Stephen, Ling, Yiwei, Takabe, Kazuaki, Okuda, Shujiro, Wakai, Toshifumi, Tsuchida, Masanori
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772517/
https://ncbi.nlm.nih.gov/pubmed/29343775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18560-y
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