Moderate decline in select synaptic markers in the prefrontal cortex (BA9) of patients with Alzheimer’s disease at various cognitive stages

Synaptic loss, plaques and neurofibrillary tangles are viewed as hallmarks of Alzheimer’s disease (AD). This study investigated synaptic markers in neocortical Brodmann area 9 (BA9) samples from 171 subjects with and without AD at different levels of cognitive impairment. The expression levels of ve...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Poirel, Odile, Mella, Sébastien, Videau, Catherine, Ramet, Lauriane, Davoli, Maria Antonietta, Herzog, Etienne, Katsel, Pavel, Mechawar, Naguib, Haroutunian, Vahram, Epelbaum, Jacques, Daumas, Stéphanie, El Mestikawy, Salah
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772053/
https://ncbi.nlm.nih.gov/pubmed/29343737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19154-y
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